Table 1.

Associated markers and alleles in the first-stage and second-stage scans

MarkerLocation (cM)*No. different alleles and genotypes observed
P
Associated allele size (bp)Statistics for the associated allele
AllelesGenotypesHWEAllele frequency differenceP§Odds ratio (95% confidence interval)
ATA29C07247.238200.9820.0142570.0541.836 (1.019-3.308)
D1S179252.1215270.0000.0381520.00212.855 (1.625-101.672)
D2S410125.188210.4190.0131600.0022.978 (1.471-6.029)
1650.0183.079 (1.221-7.762)
D2S1384200.436140.8470.0391400.1310.579 (0.295-1.133)
1440.0611.860 (0.998-3.466)
D2S434215.786170.7950.0162680.0030.376 (0.198-0.715)
D2S338250.5410260.6020.046NANANA
D3S305014.165110.4550.0342340.0961.712 (0.940-3.120)
D3S3053181.876120.0800.0042230.0102.420 (1.253-4.674)
2270.0024.712 (1.681-13.212)
D4S2394128.089240.8510.0292370.1351.619 (0.897-2.923)
2520.0152.313 (1.195-4.475)
D7S181869.566130.8130.0331850.0040.424 (0.237-0.758)
D8S592125.276120.6000.0451500.0070.450 (0.254-0.799)
D9S92532.2410300.8540.0391820.0210.446 (0.228-0.872)
D10S2327100.927130.6450.0412000.1821.535 (0.855-2.755)
2200.0362.342 (1.067-5.139)
D11S1986105.7414410.1670.0231920.0482.308 (1.019-5.226)
2230.0192.989 (1.188-7.522)
2350.0430.404 (0.174-0.939)
D13S79693.527190.2990.0571490.0472.010 (1.032-3.916)
1620.0250.400 (0.184-0.871)
D14S749108.227170.7630.0031670.1201.667 (0.897-3.098)
1710.0521.850 (1.022-3.347)
1750.0073.421 (1.373-8.525)
D16S422111.12134010.0122060.0193.434 (1.197-9.853)
D17S96927.75590.4570.0491250.0072.221 (1.251-3.944)
1290.1091.725 (0.910-3.272)
D17S80974.459260.0130.0102500.0010.468 (0.402-0.545)
D19S17868.0812310.9470.0251730.0043.279 (1.437-7.485)
D19S254100.619190.8890.0341320.0301.941 (1.095-3.442)
1360.0173.532 (1.229-10.149)
D20S10974.4715460.0710.054NANANA
D20S88772.279290.1980.0412490.0752.154 (0.949-4.887)
D22S42636.076130.0060.0132170.00026.545 (2.156-19.871)
D22S117737.478250.3790.0181800.0342.218 (1.078-4.563)
1820.0030.128 (0.028-0.579)
D22S44539.876150.1350.0221030.0060.298 (0.126-0.703)
1150.1201.571 (0.895-2.756)
D22S114230.889270.7780.0461830.0302.788 (1.101-7.062)
  • * Genetic distance (sex average) in cM from p telomere (http://research.marshfieldclinic.org/genetics/Physical_Maps/).

  • P from χ2 test (Associate program) for cases and controls combined.

  • P from Fisher's exact test for the difference in allele frequencies cases versus controls.

  • § P from Fisher's exact test for associated allele versus all other alleles pooled together.

  • Markers in the second-stage scan.