Table 1.

Univariate analysis of baseline characteristics associated with the presence of intestinal metaplasia in gastric cancer relatives

IM positive (n = 81)IM negative (n = 189)POR (95% CI)
Mean age45.8 (7.9)39.9 (8.8)<0.001
Male47 (58.0%)80 (42.3%)0.0181.88 (1.11-3.19)
Female34 (42.0%)109 (57.7%)1.0
Family members affected
    Siblings51 (63.0%)78 (41.3%)0.0012.42 (1.42-4.32)
    Parents30 (37.0%)111 (58.7%)1.0
Age of family member diagnosed to have stomach cancer (y)
    ≤4523 (28.4%)46 (24.3%)0.480.81 (0.45-1.46)
    >4558 (71.6%)143 (75.7%)1.0
Median no. siblings6 (1-11)5 (1-12)0.035
Birth order
    Youngest10 (12.3%)46 (24.3%)0.0450.45 (0.22-0.96)
Childhood water supply
    In-house tap38 (49%)126 (70%)0.0022.4 (1.38-4.15)
    Communal tap/well39 (51%)54 (30%)1.0
Childhood living area
    City51 (66%)144 (80%)0.0181.0
    Village26 (34%)35 (20%)2.04 (1.12-3.71)
Smokers17 (21.0%)36 (19.0%)0.711.13 (0.59-2.16)
Drinkers34 (42.0%)55 (29.1%)0.0391.76 (1.03-3.03)
  • Abbreviation: IM, intestinal metaplasia.