Table 1.

Characteristics of participants and biomarker levels

Cohort 1 (TRIP)
Cohort 2 (ROSCAP)
Cohort 3 (ACSS)
Cohort 4 (LLSS)
Total
Adult “healthy” smokers, 15-45 cigarettes/dAdults with heart disease, >15 cigarettes/dAdult “healthy” smokers, <15 cigarettes/dAdults with heart disease, <15 cigarettes/d
N1511528611400
Age (y)44.7 (10.5)57.9 (9.1)45.1 (11.5)67.9 (7.0)50.4 (12.2)
Gender (M/F)69:82135:1734:46*8:0246:145
Cigarettes/d24.2 (6.4)27.5 (11.6)9.2 (8.0)8.5 (4.0)21.9 (11.5)
FTND score6.1 (1.9)6.0 (2.0)2.3 (2.3)2.5 (1.9)5.2 (2.5)
CO (ppm)23.7 (10.3)23.9 (11.8)10.0 (7.9)11.1 (3.1)20.2 (12.0)
Total NNAL (pmol/mg creatinine)2.2 (1.1)2.7 (2.3)1.2 (1.1)2.2 (1.5)2.2 (1.8)
Total 1-HOP (pmol/mg creatinine)1.6 (1.1)2.2 (4.7)1.6 (1.1)1.0 (0.6)1.8 (3.2)
Total cotinine (nmol/mg creatinine)26.4 (13.3)25.1 (17.4)12.2 (11.1)17.4 (9.5)22.2 (15.7)
  • NOTE: Cell values for age, cigarettes/d, FTND score, CO, total cotinine, total NNAL, and total 1-HOP were mean (SD). Cell values for gender were counts.

  • * ACSS has six participants with missing values for gender.

  • LLSS has three participants with missing values for gender.