Table 4.

Association between regular aspirin use and endometrial cancer in obese women (BMI, >30)—Roswell Park Cancer Institute (1982-1998)

Cases, n (%)Controls, n (%)OR (95% CI)Adjusted OR (95% CI)*
Aspirin use
    No100 (59)34 (45)Ref.Ref.
Frequency of aspirin use
    Used one to six times per week47 (28)25 (33)0.64 (0.34-1.19)0.56 (0.28-1.13)
    Used more than seven times per week23 (13)16 (21)0.49 (0.23-1.03)0.40 (0.18-0.92)
Duration of aspirin use
    Used for 1 to 10 years36 (21)18 (24)0.68 (0.34-1.35)0.53 (0.25-1.15)
    Used for >10 years34 (20)23 (31)0.50 (0.26-0.97)0.46 (0.22-0.96)
Cumulative aspirin use
    Moderate use (≤10 tablet-yrs)48 (28)26 (35)0.63 (0.34-1.16)0.50 (0.22-1.13)
    High use (>10 tablet-yrs)22 (13)15 (20)0.50 (0.23-1.07)0.49 (0.24-0.99)
  • * Adjusted for age, education, and age at menopause.

  • Nonuser group served as reference group for all regression analyses. User defined as use of at least one tablet a week for at least 6 months.

  • Tablet-years defined as average number of tablets per day × years of use.