Table 5.

Relation of dietary variables to risk of breast cancer by ER status

VariableER+ cases
ER− cases
CasesRRPtrendCasesRRPtrend
Dietary calcium (mg/d)*
    ≤5003511.00621.00
    >500-≤7504710.87 (0.76-1.00)870.97 (0.69-1.34)
    >750-≤1,0002820.88 (0.75-1.03)440.84 (0.57-1.25)
    >1,000-≤1,2501160.82 (0.66-1.01)231.03 (0.64-1.69)
    >1,250630.67 (0.51-0.88)0.004110.77 (0.40-1.47)0.49
Supplemental calcium (mg/d)*
    None5961.001131.00
    <2502770.99 (0.85-1.14)440.84 (0.59-1.19)
    250-<500840.99 (0.79-1.25)191.24 (0.76-2.02)
    500-<1,0001930.98 (0.83-1.15)320.92 (0.62-1.37)
    1,000+1331.06 (0.87-1.28)0.82190.85 (0.52-1.39)0.63
Total calcium (mg/d)
    ≤5002121.00361.00
    >500-≤7503130.83 (0.69-0.98)731.20 (0.81-1.80)
    >750-≤1,0002620.87 (0.72-1.04)320.69 (0.43-1.12)
    >1,000-≤1,2501940.96 (0.79-1.18)290.97 (0.59-1.59)
    >1,250-≤1,5001040.72 (0.57-0.92)200.95 (0.55-1.66)
    >1,500-≤1,750650.71 (0.53-0.94)110.84 (0.42-1.66)
    >1,7501330.87 (0.70-1.09)0.13261.14 (0.68-1.92)0.78
Dietary vitamin D (IU/d)
    ≤1004041.00641.00
    >100-≤2005510.85 (0.75-0.97)1021.05 (0.77-1.44)
    >200-≤3002310.86 (0.73-1.02)421.06 (0.71-1.57)
    >300970.74 (0.59-0.93)0.006191.03 (0.61-1.73)0.84
Total vitamin D (IU/d)
    ≤1002431.00411.00
    >100-≤2003560.92 (0.78-1.08)731.18 (0.81-1.74)
    >200-≤3001490.88 (0.72-1.08)260.99 (0.60-1.62)
    >300-≤4001091.00 (0.80-1.26)120.74 (0.38-1.41)
    >400-≤5001260.95 (0.76-1.18)150.75 (0.41-1.37)
    >500-≤6001290.98 (0.79-1.21)221.08 (0.64-1.83)
    >600-≤700870.93 (0.73-1.19)171.15 (0.65-2.03)
    >700840.84 (0.65-1.09)0.57211.35 (0.79-2.33)0.82
Low-fat dairy (servings/d)
    <0.53071.00501.00
    0.5-13280.95 (0.81-1.11)551.03 (0.70-1.52)
    >1-24220.88 (0.76-1.03)801.13 (0.79-1.64)
    >2-3910.72 (0.56-0.92)140.82 (0.44-1.52)
    >31350.76 (0.61-0.94)0.002281.22 (0.74-2.03)0.59
Total dairy (servings/d)
    <0.51361.00251.00
    0.5-12990.98 (0.80-1.20)521.01 (0.62-1.63)
    >1-24970.88 (0.72-1.07)870.98 (0.62-1.56)
    >2-31750.71 (0.56-0.91)250.74 (0.41-1.34)
    >31760.73 (0.57-0.93)0.0003381.23 (0.70-2.15)0.77
  • NOTE: Models are adjusted for age, energy, history of breast cyst, family history of breast cancer, height, weight change from age 18 to 1992, alcohol use, parity and age at first birth, education, HRT use, and mammography history.

  • * Dietary and supplemental calcium are controlled for each other.

  • Additionally controlled for high-fat dairy intake.