Table 2.

Risks of advanced colorectal adenoma associated with tobacco use in the PLCO Cancer Screening Trial

Case (%), n = 772*Control (%), n = 777*OR (95percnt; CI)
Tobacco use
    No tobacco260 (33.7)315 (40.5)1.0
    No cigarettes, but pipes or cigars39 (5.1)43 (5.5)1.2 (0.7-1.9)
    Cigarette smoker473 (61.3)419 (53.9)1.4 (1.2-1.8)
        Long-term quitters (quit ≥10 years)272 (35.2)302 (38.9)1.1 (0.9-1.4)
        Current or recent (quit <10 years)198 (25.6)111 (14.3)2.4 (1.8-3.2)
        Light (≤20 cigarettes/d)261 (35.6)254 (34.6)1.3 (1.0-1.6)
        Heavy (>20 cigarettes/d)212 (28.9)165 (22.5)1.7 (1.3-2.2)
  • * Numbers do not add up to the total because of missing values.

  • Adjusted for gender, race, and age.