Table 2.

Reassurance outcomes 1 month post-disclosure according to genetic test results

OutcomesCarriers (a)
Noncarriers (b)
Inconclusive (c)
P*Group differences
n (%)n (%)n (%)
Cancer risk
    Very low2 (3)13 (10)19 (9)<0.0001a > b; a > c; b < c
    Low4 (5)33 (26)32 (15)
    Moderate23 (30)62 (50)91 (44)
    High27 (35)16 (13)52 (25)
    Very high21 (27)1 (1)13 (6)
Lifetime cancer risk perception (%)
    Mean ± SD53.4 ± 23.430.4 ± 21.838.0 ± 24.1<0.0001a > b; a > c; b < c
Cancer worry
    A lot less than before1 (1)52 (42)46 (22)<0.0001a > b; a > c; b < c
    A little less than before3 (4)28 (22)37 (17)
    Neither more nor less49 (62)44 (35)127 (60)
    A little more than before21 (27)1 (1)3 (1)
    A lot more than before5 (6)0 (0)0 (0)
Relief
    Not at all48 (50)5 (4)40 (17)<0.0001a < b; b > c
    Low6 (6)21 (16)54 (22)
    Moderate22 (23)30 (23)61 (25)
    Considerable20 (21)73 (57)86 (36)
Painfulness
    Not painful at all43 (44)120 (94)220 (91)<0.0001a > b; a > c
    Slightly painful31 (32)3 (2)16 (7)
    Moderately painful18 (19)5 (4)5 (2)
    Very painful5 (5)0 (0)2 (1)
Quality of life
    Decreased a lot0 (0)0 (0)2 (1)0.0019a < b; b > c
    Slightly decreased8 (8)0 (0)0 (0)
    The same79 (81)99 (78)207 (85)
    Slightly improved8 (8)9 (7)20 (8)
    Improved a lot2 (2)19 (15)15 (6)
  • * Adjusted for age (20-49, 50-69, and 70+ y), cancer status, genetic testing approach, and cancer susceptibility testing knowledge scores.

  • Based on adjusted analyses; P < 0.01.