Table 1.

Risk factors for MBC

KnownSuggestiveInconclusive
BRCA2Cowden syndromeAR gene
Family historyCirrhosisCHECK2
Klinefelter syndromeProstate cancer
ObesityProstate cancer treatment
Testicular disordersGynecomastia
    CryptorchidismOccupational exposures
    Mumps orchitisEMFs
    OrchiectomyPAHs
Radiation exposureHigh temperatures
Exogenous estrogenDiet
Alcohol