Table 4.

Overall case-control distribution of estimated haplotypes for the different DNA repair gene polymorphisms

HaplotypeCases, n (%)Controls, n (%)POR (95% CI)
XRCC3 4541-17893-18067
    CAC116 (18.7)117 (19)0.9040.98 (0.74-1.31)
    CAT0 (0)2 (0.3)0.213
    CGC2 (0.4)4 (0.7)0.4740.55 (0.11-2.85)
    TAC66 (10.7)91 (14.7)0.0340.69 (0.50-0.97)
    TAT277 (44.8)246 (39.8)0.0741.23 (0.98-1.54)
    TGC157 (25.4)156 (25.3)0.9851.00 (0.78-1.30)
    TGT0 (0)1 (0.2)0.222
618618
XRCC1 26304-26651-28152
    CAA180 (31.6)215 (37.1)0.0490.78 (0.61-1.00)
    CAG95 (16.8)93 (16)0.7061.06 (0.78-1.45)
    CGA13 (2.2)4 (0.8)0.0432.91 (0.98-8.59)
    CGG243 (42.8)218 (37.7)0.0741.24 (0.98-1.57)
    TAA2 (0.3)0 (0)0.2419.44 (0.10-934.71)
    TAG35 (6.2)49 (8.4)0.1470.72 (0.46-1.13)
568580
XPD/ERCC1 23591-35931-19007
    AAC27 (5.9)31 (6.3)0.8060.93 (0.55-1.60)
    AAT4 (1)2 (0.4)0.3012.35 (0.44-12.44)
    ACC81 (18.1)100 (20.4)0.370.86 (0.62-1.19)
    ACT69 (15.3)70 (14.3)0.6871.08 (0.75-1.54)
    GAC41 (9)53 (10.8)0.3760.82 (0.54-1.27)
    GAT189 (42.1)207 (42.3)0.9410.99 (0.76-1.28)
    GCC14 (3.2)8 (1.5)0.0922.11 (0.87-5.15)
    GCT25 (5.4)19 (3.9)0.2741.40 (0.76-2.59)
450490
ERCC4 30028-30147
    CA126 (30.9)123 (28.9)0.5261.10 (0.82-1.48)
    CG11 (2.7)12 (2.8)0.9150.95 (0.42-2.19)
    TA271 (66.4)291 (68.3)0.5610.92 (0.69-1.23)
408426
  • NOTE: ORs and 95% CIs have been reported for all the groups.