Table 1.

SNPs included in the MDR analysis

GeneSNPPositionVariationMinor allele
AlleleFrequency in casesFrequency in controls
TLR6-1-10rs5743604−833T/CC0.240.20
TLR2rs38041001,349T/CC0.070.07
TLR3rs5743305−8,411T/AA0.340.36
rs3775296−7C/AA0.180.20
rs57433132,593C/TT0.180.19
TLR4rs1927914−2,026A/GG0.330.33
IIPGA-TLR4-2856−1,607T/CC0.150.14
IIPGA-TLR4-182083,747A/CC0.020.02
rs49867908,551A/GG0.050.06
IIPGA-TLR4-140789,614G/AA0.050.06
rs787378412,185G/CC0.140.14
IIPGA-TLR4-1584411,380G/CC0.130.11
TLR5IIPGA-TLR5-5187−27,694C/TT0.490.47
rs20724931,774A/GG0.140.16
rs57441741,845T/CC0.480.47
rs10539542,522A/GG0.080.08
TLR7rs2302267−120T/GG0.060.05
rs1790194,271C/AA0.230.23
rs17900817,961A/TT0.130.13
TLR8rs1548731−558C/TT0.260.27
rs48308063,467C/TT0.390.38
rs57440686,553C/TT0.160.17
TLR9rs187084−1,486T/CC0.440.44
IL-1RNrs8789722,117A/CC0.270.28
rs3159348,110T/CC0.190.20
rs31595114,991C/GG0.320.34
rs308726319,172A/GG0.090.10
TIRAPrs42514319,537T/CC0.370.37
TIRAP_1411514,115T/GG0.240.21
TIRAP_1767817,678G/AA0.050.05
MyD88rs4988453−938C/AA0.060.07
IRAK1rs10597036,434C/TT0.130.14
rs302788989,373T/GG0.180.19
IRAK4rs4251571−2,001A/GG0.020.02
rs42514877,987G/CC0.020.01
rs425154518,380G/AA0.100.10
TNFrs2799724−1,037C/TT0.070.07
rs3093662670A/GG0.030.03
rs30936641,123A/GG0.070.08
rs30936651,872A/CC0.010.02
IL-6rs1800797−661G/AA0.510.54
rs1800796−636G/CC0.040.05
rs1800795−237G/CC0.490.48
rs14743481,027G/CC0.510.52
rs20698453,268G/AA0.520.51
rs20698604,157A/TT0.010.01
IL-10rs1800896−1,117A/GG0.470.49
rs1800872−627C/AA0.260.25
rs15542861,547C/TT0.210.19
rs30245092,483CT/CC0.060.08
rs30245055,876C/TT0.130.13
COX2rs2745557201T/CT0.160.15
rs204323,099T/GG0.870.84
rs46482763,934T/CC0.100.12
rs52756,364T/CC0.350.36
rs6894708,364C/TT0.020.04
MIC1rs10585872,433G/CC0.270.29
  • NOTE: For SNPs which have not been assigned an rs identifier, we used either an IIPGA identifier if available or the relative position of the SNP in the gene (from the transcription site). The relative position of TLR4 is based on isoform A. The relative position of IL-1RN is based on isoform 3.