Table 4.

Association between IL-8 genotype and histologic scores in noncancerous gastric mucosa adjacent to cancer

IL-8 −251 genotype (n)Histologic score
Neutrophil infiltrationMononuclear cell infiltrationAtrophyIntestinal metaplasia
A/A (21)1.91 ± 0.44*1.67 ± 0.912.00 ± 0.951.67 ± 1.07
A/T (100)1.58 ± 0.781.68 ± 0.721.67 ± 1.021.44 ± 1.09
A carrier (121)1.64 ± 0.741.68 ± 0.761.73 ± 1.011.48 ± 1.08
T/T (73)1.47 ± 0.781.69 ± 0.741.69 ± 0.971.41 ± 0.93
  • NOTE: A carrier, A/A + A/T. Scores shown are mean ± SD.

  • * P = 0.02, compared among A/A, A/T, and T/T genotype by the Kruskal-Wallis rank test.

  • P = 0.09, compared with A carrier and T/T genotypes by the Mann-Whitney U test.