Table 4.

Multivariate breast cancer risk and FOK1 polymorphism by 25(OH)D, 1,25(OH)2D and vitamin D intake

FFFfFF
25(OH)D* (671 cases/658 controls)
    ≤Median1.0 (referent)1.12 (0.77-1.61)1.44 (0.86-2.41)
    >Median0.84 (0.56-1.25)0.88 (0.60-1.30)1.27 (0.76-2.13)
P for interaction = 0.95
1,25(OH)2D (607 cases/576 controls)
    ≤Median1.0 (referent)1.16 (0.79-1.71)1.65 (1.00-2.72)
    >Median0.87 (0.57-1.34)0.97 (0.66-1.42)1.45 (0.82-2.57)
P for interaction = 0.94
Vitamin D intake (1,218 cases/1,663 controls)
    ≤Median1.0 (referent)1.03 (0.80-1.34)0.99 (0.69-1.42)
    >Median0.84 (0.65-1.10)0.98 (0.76-1.25)1.39 (0.99-1.94)
P for interaction = 0.05
  • NOTE: Adjusted for the same factors as multivariate OR in Table 2.

  • * Batch-specific medians: batch 1, 30; batch 2, 37; batch 3, 27.5 ng/mL.

  • Median, 33.1 ng/mL.

  • Median, 292 IU/d.