Table 1.

Mean (95% CL) for main characteristics and plasma IGF-I, IGFBP-3, and IGFMR levels from 955 MEC participants by sex and racial/ethnic group

Native HawaiianAfrican AmericanJapaneseLatinoWhiteP*
Females
    No. subjects (% women)77 (17)96 (21)100 (22)99 (21)93 (20)
    Age, y66.7 (65.1, 68.3)67.6 (66.2, 69.1)69.1 (67.7, 70.6)67.5 (66.1, 69.0)68.2 (66.8, 69.7)0.23
    Height, in.63.8 (63.3, 64.3)64.3 (63.8, 64.8)60.6 (60.2, 61.1)62.7 (62.2, 63.2)64.5 (64.0, 65.0)<0.0001
    Weight, lb.166 (159, 173)172 (166, 179)125 (119, 132)162 (155, 168)155 (148, 161)<0.0001
    BMI, kg/m228.7 (27.5, 29.9)29.3 (28.3, 30.4)24.0 (23.0, 25.1)29.1 (28.0, 30.1)26.2 (25.1, 27.3)<0.0001
    IGF-I, ng/mL144 (131, 159)157 (144, 171)147 (135, 160)122 (112, 133)142 (130, 155)0.002
    IGFBP-3, ng/mL2,854 (2,641, 3,084)2,571 (2,399, 2,756)2,871 (2,682, 3,073)2,218 (2,072, 2,375)2,641 (2,641, 3,041)<0.0001
    IGFMR0.19 (0.17, 0.20)0.23 (0.21, 0.24)0.19 (0.18, 0.20)0.21 (0.19, 0.22)0.19 (0.17, 0.20)0.0006
Males
    No. subjects (% men)98 (20)98 (20)98 (20)99 (20)97 (20)
    Age, y64.4 (62.7, 66.2)65.1 (63.3, 66.9)65.2 (63.4, 67.0)65.2 (63.4, 67.0)65.3 (63.5, 67.1)0.96
    Height, in.68.9 (68.4, 69.4)70.0 (69.5, 70.5)66.2 (65.7, 66.8)68.0 (67.4, 68.5)69.3 (68.8, 69.8)<0.0001
    Weight, lb.197 (190, 203)195 (189, 202)156 (150, 163)178 (172, 185)188 (181, 194)<0.0001
    BMI, kg/m229.1 (28.2, 30.0)28.0 (27.1, 28.9)25.1 (24.2, 26.0)27.2 (26.3, 28.1)27.5 (26.6, 28.4)<0.0001
    IGF-I, ng/mL190 (174, 207)175 (160, 191)177 (162, 193)167 (153, 182)180 (165, 197)0.37
    IGFBP-3, ng/mL2,713 (2,531, 2,908)2,375 (2,216, 2,546)2,652 (2,474, 2,843)2,481 (2,316, 2,659)2,769 (2,582, 2,969)0.01
    IGFMR0.26 (0.24, 0.28)0.27 (0.26, 0.29)0.25 (0.23, 0.27)0.25 (0.23, 0.27)0.24 (0.23, 0.26)0.14
  • * P for testing homogeneity of means across race/ethnicity derived from ANOVA and analysis of covariance models.