Table 1.

Clinicopathologic characteristics according to COX-2 expression

CharacteristicsCOX-2 expression
P*
NegativePositive
Patients [n (%)]125 (82.2)27 (17.8)
Age, y (mean ± SD)49.8 ± 11.055.9 ± 10.00.009
Parity (mean ± SD)2.1 ± 1.62.5 ± 2.0NS
Body mass index, kg/m2 (mean ± SD)25.5 ± 4.526.3 ± 3.7NS
Menopausal status [n (%)]
    Premenopausal62 (91.2)6 (8.8)0.009
    Postmenopausal63 (75.0)21 (25.0)
Histotype [n (%)]
    Endometrioid121 (82.3)26 (17.7)NS
    Others4 (80.0)1 (20.0)
International Federation of Gynecology and Obstetrics stage [n (%)]
    I, II103 (82.4)22 (17.6)NS
    III, IV22 (81.5)5 (18.5)
Grade [n (%)]
    174 (84.1)14 (15.9)NS
    2 or 314 (15.9)13 (20.3)
Lymph node metastasis [n (%)]
    Negative92 (83.6)18 (16.4)NS
    Positive10 (66.7)5 (33.3)
Myometrial invasion [n (%)]
    Less than half97 (84.3)18 (15.7)NS
    More than half28 (75.7)9 (24.3)
p53 overexpression [n (%)]
    No100 (80.0)25 (20.0)NS
    Yes21 (77.8)6 (22.2)
  • * By the t test or the χ2 test.

  • Papillary serous or clear cell type.

  • Lymph node dissection was not done in 27 cases.