Table 2.

The association of serum EBV antibody titer patterns with skin nonreactivity to PPD

Antibody Titer/Pattern% Specified Titer Level by PPD Status
OR (95% CI) for PPD Nonreactivity, Adjusted for Age, Gender, and Smoking History
Nonreactive (n = 50)Reactive (n = 100)
Anti-EBNA
    ≤1:8018.015.01.2 (0.5-3.3)
    1:160-1:32060.058.01.0
    ≥1:64022.027.00.6 (0.3-1.5)
Anti-VCA
    ≤1:32022.034.01.0
    1:640-1:1,28054.046.02.2 (0.9-5.3)
    ≥1:2,56024.020.02.1 (0.7-6.0)
Anti-EA
    Seronegative (<1:5)82.088.01.0
    Seropositive (≥1:5)18.012.01.7 (0.6-4.5)
Joint classification of anti-VCA* and anti-EBNA
    Anti-VCA normal, anti-EBNA normal12.027.01.0
    Anti-VCA normal, anti-EBNA low10.07.03.7 (0.8-17.6)
    Anti-VCA high, anti-EBNA normal70.058.03.4 (1.2-9.9)
    Anti-VCA high, anti-EBNA low8.08.03.7 (0.7-18.7)
  • * Anti-VCA titers are “normal” if ≤1:320 and “high” if ≥1:640.

  • Anti-EBNA titers are “normal” ≥1:160 and “low” if ≤1:80.