Table 2.

Adjusted OR and 95% CI for association with Hodgkin's lymphoma risk by age group

Risk Factor (Comparison Groups)Ages 15-54 y (470 Cases, 557 Controls), OR* (95% CI)Ages 55-79 y (95 Cases, 122 Controls), OR* (95% CI)P for Test of Heterogeneity by Age
Demographics
    Race (Black/White)0.91 (0.51-1.62)0.75 (0.49-1.15)0.03
    Race (other/White)0.64 (0.12-3.48)7.38 (0.86-63.15)0.03
    Religion (Protestant/Catholic)0.77 (0.57-1.05)0.73 (0.39-1.37)0.34
    Religion (Jewish/Catholic)1.77 (1.01-3.13)0.60 (0.17-2.13)0.34
    Subject education (less than high school/high school/college/advanced degree)0.82 (0.70-0.96)0.80 (0.59-1.09)0.92
    Median household income (quartiles 1-4)1.02 (0.91-1.14)0.92 (0.72-1.18)0.44
    Percentage below poverty level (quartiles 1-4)0.99 (0.89-1.11)1.05 (0.81-1.35)0.62
Childhood social factors
    Maternal education (less than high school/high school/college/advanced degree)0.95 (0.82-1.10)0.52 (0.32-0.83)0.01
    Paternal education (less than high school/high school/college/advanced degree)1.02 (0.89-1.17)0.64 (0.44-0.95)0.03
    Number of siblings (0-1/2/3-4/≥5)0.93 (0.82-1.05)1.21 (0.96-1.53)0.05
    Number of regular childhood playmates (0-5/6-10/≥11)1.02 (0.87-1.20)0.81 (0.56-1.17)0.14
    Housing density in childhood (1-family/2-family/3-family/≥4-family)1.10 (0.97-1.25)0.89 (0.70-1.12)0.10
    Housing ownership in childhood (own/rent)0.92 (0.68-1.25)1.20 (0.69-2.08)0.44
    Nursery school or day care attendance (yes/no)0.87 (0.68-1.13)0.63 (0.19-2.15)0.50
    Nursery school or day care attendance for <1 year (yes/no)1.02 (0.75-1.40)0.26 (0.03-2.29)0.16
    Nursery school or day care attendance for ≥1 year (yes/no)0.64 (0.45-0.92)1.20 (0.25-5.64)0.55
Medical history
    History of mononucleosis (yes/no)0.92 (0.65-1.31)0.78 (0.24-2.48)0.82
    History of allergy (yes/no)0.93 (0.71-1.21)0.64 (0.36-1.15)0.31
    History of asthma (yes/no)0.90 (0.64-1.27)0.54 (0.22-1.32)0.32
    History of autoimmune disease (yes/no)1.57 (0.76-3.28)0.90 (0.28-2.85)0.57
    Family history of any cancer (yes/no)1.43 (1.10-1.87)0.68 (0.36-1.29)0.05
    Family history of hematopoietic cancer (yes/no)2.06 (1.10-3.87)1.76 (0.58-5.35)0.86
Other factors
    Cigarette smoking (≥10 packs in lifetime; yes/no)1.31 (1.03-1.69)1.12 (0.61-2.06)0.56
    Any tobacco product (e.g., cigarettes, cigars, and tobacco; yes/no)1.30 (1.01-1.67)1.31 (0.65-2.63)0.77
    Job with wood or wood products (yes/no)1.39 (0.98-1.97)2.30 (0.87-6.07)0.63
    Hobby with wood or wood products (yes/no)0.91 (0.67-1.24)0.80 (0.40-1.59)0.50
  • * Adjusted for sex and state. ORs for binary risk factors compare the first category to the second category (e.g., yes versus no); ORs for ordinal risk factors compare increasing levels.

  • U.S. Census data based on subjects' census tract of residence.