Table 4.

Relative risk for adenoma of the distal colon and rectum according to quintiles of dietary glycemic index, dietary glycemic load, and carbohydrate intake

Quintiles of energy-adjusted dietary intake
1 (lowest)2345 (highest)Ptrend
Glycemic index
    Distal colon (n = 1,277)
        Age-adjusted11.10 (0.92-1.31)0.98 (0.82-1.17)0.89 (0.74-1.07)1.13 (0.95-1.35)0.72
        Multivariate*11.15 (0.97-1.37)1.04 (0.86-1.25)0.94 (0.77-1.14)1.20 (0.98-1.46)0.36
    Rectum (n = 504)
        Age-adjusted10.90 (0.68-1.18)0.99 (0.75-1.29)0.87 (0.65-1.14)0.93 (0.71-1.23)0.57
        Multivariate10.94 (0.71-1.24)1.03 (0.78-1.35)0.88 (0.66-1.19)0.90 (0.66-1.22)0.47
Glycemic load
    Distal colon (n = 1,277)
        Age-adjusted10.89 (0.74-1.06)0.93 (0.78-1.11)0.89 (0.74-1.06)0.73 (0.61-0.88)0.002
        Multivariate*10.98 (0.81-1.18)1.10 (0.91-1.34)1.09 (0.89-1.33)0.95 (0.76-1.19)0.96
    Rectum (n = 504)
        Age-adjusted10.93 (0.70-1.22)1.03 (0.79-1.35)0.91 (0.69-1.20)0.76 (0.57-1.02)0.08
        Multivariate10.96 (0.71-1.29)1.12 (0.83-1.51)1.02 (0.74-1.39)0.85 (0.60-1.19)0.44
Carbohydrate intake
    Distal colon (n = 1,277)
        Age-adjusted10.82 (0.68-0.98)0.91 (0.77-1.08)0.82 (0.69-0.98)0.69 (0.58-0.83)0.002
        Multivariate*10.88 (0.72-1.06)1.05 (0.86-1.28)1.00 (0.80-1.24)0.90 (0.71-1.15)0.69
    Rectum (n = 504)
        Age-adjusted10.99 (0.75-1.30)0.96 (0.73-1.27)0.96 (0.73-1.27)0.77 (0.58-1.04)0.10
        Multivariate11.01 (0.75-1.36)1.04 (0.76-1.43)1.09 (0.78-1.52)0.89 (0.61-1.30)0.71
  • * Multivariate model included the variables listed in Table 3.