Table 1.

Genotype distribution, ORs, and 95% CIs for the association between PGR +331 polymorphism and postmenopausal breast cancer

GenotypeCases (n = 479)Controls (n = 494)OR* (CI)OR (CI)
G/G425 (88.7)445 (90.1)
G/A53 (11.1)48 (9.7)
A/A1 (0.2)1 (0.2)
G/G425 (88.7)445 (90.1)1.01.0
G/A + A/A54 (11.3)49 (9.9)1.19 (0.79-1.79)1.15 (0.74-1.76)
  • * OR adjusted for birth date, race/ethnicity, and date of blood draw.

  • OR adjusted for birth date, race/ethnicity, date of blood draw, education, personal history of breast cyst, family history of breast cancer, age at menarche, parity, age at first birth, age at menopause, BMI, and type of HRT use.