Table 2.

Distribution of serum vitamin D metabolites and their association with advanced distal colorectal adenoma

VariableNumber of subjects
Mean ± SE
OR95% CIPtrend
CasesControlsCasesControls
Serum 25(OH) vitamin D (ng/ml)
    Overall39439727.0 ± 0.4928.3 ± 0.490.870.75–1.010.06
        Female12312425.1 ± 0.8829.3 ± 0.870.590.45–0.780.0002
        Male27127327.9 ± 0.5927.8 ± 0.591.020.84–1.230.85
        Age, 55–64 yr26328027.7 ± 0.6928.6 ± 0.700.910.76–1.100.33
        Age, 65–74 yr13111725.4 ± 1.1728.0 ± 1.190.720.54–0.950.02
Serum 1,25(OH)2 vitamin D (pg/ml)
    Overall39439736.3 ± 0.5036.0 ± 0.501.030.89–1.190.66
        Female12312437.1 ± 0.9137.9 ± 0.900.920.72–1.160.46
        Male27127335.9 ± 0.6135.1 ± 0.611.100.91–1.330.35
        Age, 55–64 yr26328036.4 ± 0.7135.6 ± 0.721.080.91–1.280.39
        Age, 65–74 yr13111736.1 ± 1.2136.9 ± 1.240.950.71–1.280.75
  • Note: Mean values are adjusted for age, gender, ethnic origin, study center, and months of blood draw. 95% CI, 95% confidence interval. OR for serum vitamin D levels per 10 units increase. ORs adjusted for age, gender, ethnic origin, study center, and month of blood draw.