Table 2.

Associations between aspirin, NSAIDs, and rectal cancer

Men
Women
Everyone
CasesControlsOR (95% CI)CasesControlsOR (95% CI)OR (95% CI)
Aspirin
    Never3784441.03063601.01.0
    Current/ever1812270.9 (0.7–1.2)861710.6 (0.4–0.8)0.8 (0.6–0.9)
    Never3784441.03063601.01.0
    Current1511900.9 (0.7–1.2)621320.6 (0.4–0.8)0.8 (0.6–1.0)
    Ever use29350.9 (0.5–1.6)20360.7 (0.4–1.2)0.8 (0.5–1.2)
NSAIDs
    Never4675121.02943581.01.0
    Current/ever911590.6 (0.5–0.8)981740.6 (0.5–0.9)0.6 (0.5–0.8)
    Never4675121.02943581.01.0
    Current671190.6 (0.4–0.8)711270.6 (0.4–0.9)0.6 (0.5–0.8)
    Ever use24380.7 (0.4–1.2)27420.8 (0.5–1.4)0.8 (0.5–1.1)
Either aspirin or NSAIDs
    Never3183461.02312541.01.0
    Current/ever2413470.8 (0.6–1.0)1622780.6 (0.5–0.8)0.7 (0.6–0.8)
    Never3173431.02303531.01.0
    Current2002690.8 (0.6–1.0)1192260.6 (0.4–0.7)0.7 (0.6–0.8)
    Ever use42610.7 (0.5–1.1)44530.9 (0.5–1.4)0.8 (0.6–1.1)
  • Note: ORs and 95% CIs are adjusted for age, BMI, physical activity, cigarette smoking, energy intake, dietary fiber, and calcium.