Table 1.

Description of population

Colon
Rectal
Cases [n (%)]Controls [n (%)]Cases [n (%)]Controls [n (%)]
Age
    <50108 (8.0)163 (10.6)147 (15.4)178 (14.8)
    50–59265 (19.7)267 (17.3)248 (26.1)304 (25.2)
    60–69475 (35.0)546 (35.4)319 (33.5)392 (32.5)
    70–79498 (37.0)568 (36.8)238 (25.0)331 (27.5)
Gender
    Male756 (56.2)845 (54.7)559 (58.7)673 (55.9)
    Female590 (43.8)699 (45.3)393 (41.3)532 (44.2)
Education level
    Below high school217 (16.1)193 (12.5)104 (10.9)127 (10.6)
    High school372 (27.6)431 (27.9)226 (23.7)270 (22.4)
    College607 (45.1)708 (45.9)473 (49.7)578 (48.0)
    Graduate school150 (11.1)211 (13.7)149 (15.7)229 (19.0)
Aspirin use (ever on regular basis)
    Yes362 (26.90)514 (33.3)267 (28.1)398 (33.1)
    No984 (73.1)1029 (66.7)684 (71.9)804 (66.9)
Ibuprofen use (ever on regular basis)
    Yes259 (19.3)383 (24.9)189 (19.9)333 (27.7)
    No1082 (80.7)1156 (75.1)761 (80.1)870 (72.3)
VDR BsmI
    bb433 (37.1)410 (35.6)308 (40.0)368 (37.7)
    Bb568 (48.7)538 (46.7)348 (45.2)465 (47.6)
    BB165 (14.2)205 (17.8)114 (14.8)144 (14.7)
VDR poly(A)
    LL373 (37.8)406 (35.0)310 (39.9)373 (37.5)
    LS479 (48.6)545 (47.0)351 (45.1)466 (46.9)
    SS134 (13.6)208 (18.0)117 (15.0)155 (15.6)
IRS1
    GG998 (84.5)1031 (88.4)681 (87.2)873 (88.4)
    GR/RR183 (15.5)135 (11.6)100 (12.8)115 (11.6)
IRS2
    GG467 (46.5)481 (41.2)325 (42.4)421 (42.8)
    GD409 (40.7)552 (47.3)343 (44.8)423 (43.0)
    DD128 (12.8)134 (11.5)98 (12.8)139 (14.1)
IGF
    192/192433 (37.0)479 (40.9)327 (42.1)399 (40.5)
    192/no 192567 (48.5)533 (45.5)348 (44.8)450 (45.7)
    no 192170 (14.5)159 (13.6)102 (13.1)136 (13.8)
IGFBP3
    CC303 (25.9)340 (29.2)221 (28.4)267 (27.0)
    CA613 (52.4)565 (48.6)384 (49.3)517 (52.3)
    AA253 (21.6)258 (22.2)174 (22.3)205 (20.7)