Table 3.

Associationsabetween recent alcohol consumption and postmenopausal breast cancer among selected subgroups in the CTS

SubgroupAlcohol consumption
Nondrinkers<20 g/day≥20 g/day
No family history of breast cancer1.0 [246]1.04 (0.89–1.22) [433]1.42 (1.13–1.79) [105]
Breast cancer in a first degree relative1.0 [65]0.94 (0.69–1.29) [106]0.92 (0.54–1.57) [18]
BMI < 27.3 (normal or only marginally overweight)1.0 [195]1.09 (0.92–1.30) [404]1.40 (1.09–1.79) [99]
BMI ≥ 27.3 (overweight or obese)1.0 [116]0.88 (0.69–1.13) [135]1.10 (0.71–1.72) [24]
Parous1.0 [239]1.10 (0.94–1.29) [443]1.41 (1.11–1.80) [95]
Nulliparous1.0 [72]0.77 (0.56–1.04) [96]1.02 (0.65–1.59) [28]
Physically activeb1.0 [167]1.09 (0.91–1.32) [365]1.33 (1.02–1.74) [81]
Not physically active1.0 [144]0.93 (0.75–1.17) [174]1.34 (0.95–1.90) [42]
No history of benign breast disease (BBD)1.0 [228]1.01 (0.85–1.19) [384]1.26 (0.99–1.64) [85]
Biopsy indicating BBD1.0 [83]1.07 (0.82–1.40) [155]1.44 (0.97–2.13) [38]
No HRT1.0 [68]0.99 (0.72–1.37) [87]0.98 (0.55–1.73) [15]
Estrogen only1.0 [98]0.98 (0.76–1.27) [157]1.24 (0.84–1.84) [36]
Estrogen plus progestin1.0 [130]1.09 (0.88–1.35) [282]1.51 (1.13–2.03) [70]
  • a RR (95% CI) and [number of breast cancer cases with complete data on all covariates of interest]; adjusted for age, race/ethnicity, caloric intake, age at menarche, family history of breast cancer, BMI, nulliparity/age at FFTP, physical activity, and duration of ERT use.

  • b Defined as 1.5 or more hours per week of strenuous or moderate exercise during the past 3 years.