Table 1.

RRs and 95% CIs for invasive breast cancer associated with alcohol consumption at different periods in life, by menopausal status at the time of joining the CTS cohort

Alcohol consumption (g/day)Pre/perimenopausal women
Postmenopausal women
CasesaPerson-yearsRRb95% CICasesPerson-yearsRR95% CI
Past year
    Nondrinkers9560,2211.031165,9751.0
        <55333,1930.930.66–1.3018136,9781.030.86–1.24
        5–95533,4371.050.75–1.4715030,4861.040.86–1.27
        10–144223,7761.090.75–1.5712624,5001.080.88–1.33
        15–192711,8241.280.83–1.978218,2790.910.71–1.16
        ≥202310,2641.210.76–1.9212319,0051.321.06–1.63
Age 30–35c
    Nondrinkers6634,9361.024955,6711.0
        <54723,9940.980.67–1.4319636,0361.221.01–1.47
        5–96727,0361.270.90–1.7917738,0481.040.84–1.26
        10–144318,1511.230.84–1.8213023,3411.281.03–1.59
        15–19218,9851.150.70–1.897514,3831.170.90–1.51
        ≥20179,0850.910.53–1.577915,0601.200.93–1.55
Age 18–22d
    Nondrinkers11259,2831.049797,3731.0
        <55430,8380.970.70–1.3417133,8241.030.86–1.23
        5–95930,9781.120.81–1.5310425,7760.850.68–1.05
        10–143922,1921.100.76–1.608215,2501.170.92–1.48
        15–1998,5840.720.37–1.43255,2831.010.68–1.52
        ≥201215,2410.620.34–1.13275,6981.070.72–1.58
Change in consumptionc
Past year
Age 30–35
    NoneNone5630,6181.017643,1081.0
    None<20259,6781.280.79–2.059316,6161.351.05–1.74
    <20None104,1671.200.61–2.356611,7031.280.96–1.70
    <20<2014364,8181.160.85–1.5941384,6131.190.99–1.42
    None/<20≥20e459,1421.210.87–1.68
    ≥20None/<20103,8201.220.62–2.407911,4381.581.21–2.07
    ≥20≥20124,1651.540.82–2.90345,9181.420.98–2.06
Change in consumptiond
Past year
Age 18–22
    NoneNone6036,8051.022447,6311.0
    None<203118,6201.110.72–1.725913,9630.960.72–1.28
    <20None4721,0401.100.75–1.6223644,0041.090.91–1.31
    <20<2011568,0591.060.77–1.4525755,8571.020.85–1.23
    None/<20≥201012,8910.650.33–1.28184,3431.030.63–1.67
    ≥20None/<20207,3511.340.80–2.2410316,0501.331.05–1.68
    ≥20≥20e91,3551.440.74–2.82
  • a Case counts and total person-years reflect women with complete data on all covariates of interest.

  • b Adjusted for age, race/ethnicity, caloric intake, family history of breast cancer, age at menarche, nulliparity/age at FFTP, physical activity, BMI, and duration of ERT use.

  • c Among women >35 years old at baseline.

  • d Among women >22 years old at baseline.

  • e Five or fewer cases.