Table 1.

Frequency of IGF-I and IGFBP-3 variants, and ORs and 95% CIs for their association with CaP in sibling-based study

Gene variant	Cases (%)	Controls (%)	OR (95% CI)^a
IGF-I (CA)_n repeats^b
≤17	30 (3.4)	38 (4.0)
18^c	65 (7.4)	67 (7.0)	0.97 (0.67–1.41)
19	548 (62.3)	586 (61.2)	1.0 (referent)
20^d	170 (19.3)	180 (18.8)	0.99 (0.78–1.27)
≥21	67 (7.7)	87 (9.1)

IGFBP-3 (−202)
CC	126 (28.6)	115 (29.0)	1.0 (referent)
AC	217 (49.3)	225 (47.0)	0.81 (0.51–1.30)
AA	97 (22.1)	139 (24.0)	0.76 (0.40–1.44)

↵a Adjusted for age.
↵b Allele counts from chromosomes (twice the total sample size).
↵c OR and 95% CI for ≤18 repeats.
↵d OR and 95% CI for ≥20 repeats.