Table 3

Genotype distributions of study participants, stratified by race

GenotypeNon-Hispanic whiteOtheraPb
n (%)n (%)
CYP17
 A1/A153 (35.8)8 (36.4)
 A1/A267 (45.3)10 (45.4)0.99
 A2/A228 (18.9)4 (18.2)
CYP19 7r(−3)
 No copies58 (39.2)11 (50.0)
 7r(−3)/X75 (50.7)10 (45.5)0.59c
 7r(−3)/7r(−3)15 (10.1)1 (4.5)
CYP19 7r
 Noncarrier118 (79.7)10 (45.4)0.001c
 Carrier30 (20.3)12 (54.6)
CYP19 8r
 Noncarrier115 (77.7)20 (90.9)0.26c
 Carrier33 (22.3)2 (9.1)
CYP19 11r
 No copies57 (38.5)12 (54.5)
 11r/X73 (49.3)9 (40.9)0.35c
 11r/11r18 (12.2)1 (4.6)
CYP1B1
 Val/Val26 (17.6)4 (18.2)
 Val/Leu76 (51.3)9 (40.9)0.65c
 Leu/Leu46 (31.1)9 (40.9)
COMT
 Val/Val40 (27.0)9 (40.9)
 Val/Met78 (52.7)8 (36.4)0.29c
 Met/Met30 (20.3)5 (22.7)
  • a Includes American Indian, Asian/Pacific Islander, African American, Hispanic white, and other.

  • b χ2 test for differences in genotype across race.

  • c Used Fisher’s exact test because of small cell sizes.