Table 2

Comparison of lifetime risks for the imaginary sister: Estimations by the Claus tables, the Claus model, the BRCA1/2 model, and the BRCA1/2/u model

Claus tables
≤10%10–20%20–30%>30%Total
Claus modela
 ≤10%13275045
 10–20%23417962
 20–30%11012730
 >30%29143459
 Total18804850196
BRCA1/2b
 ≤10%4176027
 10–20%12442719102
 20–30%085720
 >30%211102447
 Total18804850196
BRCA1/2/uc
 ≤10%7100010
 10–20%83711359
 20–30%132282586
 >30%2892241
 Total18804850196
  • a The Claus table and the Claus model have 47% agreement (Spearman rank correlation, 0.58).

  • b The Claus tables and the BRCA1/2 model have 39% agreement (Spearman rank correlation, 0.38).

  • c The Claus tables and the BRCA1/2/u model have 48% agreement (Spearman rank correlation, 0.52).