Table 4.

Association between diplotypes of CASR and advanced colorectal adenomas

CASR diplotypeCases (n)Controls (n)OR (95% CI)
000/0004103691.00
000/1001321510.80 (0.60-1.06)
000/01071840.79 (0.55-1.13)
000/00139640.56 (0.36-0.88)
All other diplotypes*63610.99 (0.67-1.46)
  • NOTE: ORs adjusted for age, gender, ethnic origin, and study center. 000 = A986, R990, Q1011; 100 = 986S, R990, Q1011; 010 = A986, 990G, Q1011; 001 = A986, R990, 1011E.

  • * Frequency of any of the other six possible diplotypes was <2.5%