Table 3.

Haplotype frequency of CASR reconstructed from genotype data

HaplotypeCases, frequency (SE)Controls, frequency (SE)
000 = A986, R990, Q10110.743 (0.0025)0.741 (0.0026)
100 = 986S, R990, Q10110.128 (0.0010)0.145 (0.0011)
010 = A986, 990G, Q10110.081 (0.0021)0.085 (0.0024)
001 = A986, R990, 1011E0.048 (0.0012)0.056 (0.0007)
  • NOTE: A986S and R990G, r2 = 0.018, D′ = −0.99, P = 0.002; A986S and Q1011E, r2 = 0.010, D′ = −1.00, P = 0.0003; R990G and Q1011E, Q1011E, r2 = 0.004, D′ = −0.86, P = 0.13.