Table 2.

Association between genotypes of CASR and advanced colorectal adenomas

CASR genotypeCases, n (%)Controls, n (%)OR (95% CI)
A986S
GG545 (76.8)531 (73.1)1.00
GT148 (20.9)179 (24.7)0.82 (0.64-1.06)
TT17 (2.4)16 (2.2)1.07 (0.52-2.19)
R990G
AA590 (85.1)580 (83.9)1.00
AG94 (13.6)104 (15.1)0.92 (0.68-1.26)
GG9 (1.3)7 (1.0)1.17 (0.36-3.79)
Q1011E
CC646 (91.1)647 (89.1)1.00
CG58 (8.2)77 (10.6)0.76 (0.53-1.11)
GG5 (0.7)2 (0.3)2.35 (0.44-12.6)
  • NOTE: ORs adjusted for age, gender, ethnic origin, and study center.