Relative risk of colorectal cancer by genotype at subsites of colorectum
| Genotype | Caecum/ascendens | Transversum/descendens | Sigmoideum | Rectum | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases/control | OR (95% CI) | Cases/control | OR (95% CI) | Cases/control | OR (95% CI) | Cases/control | OR (95% CI) | |||||||||
| MTHFR 677 | ||||||||||||||||
| CC | 210/209 | 1 | 145/140 | 1 | 301/309 | 1 | 411/396 | 1 | ||||||||
| CT | 150/157 | 0.95 (0.71-1.29) | 135/127 | 1.04 (0.73-1.48) | 245/233 | 1.10 (0.87-1.41) | 341/345 | 0.96 (0.78-1.18) | ||||||||
| TT | 38/36 | 1.09 (0.62-1.91) | 21/38 | 0.57 (0.32-1.01) | 46/60 | 0.80 (0.52-1.23) | 52/73 | 0.69 (0.47-1.02) | ||||||||
| MTR 2756 | ||||||||||||||||
| AA | 262/264 | 1 | 191/183 | 1 | 403/383 | 1 | 544/528 | 1 | ||||||||
| AG | 119/127 | 0.95 (0.70-1.29) | 93/107 | 0.85 (0.61-1.18) | 177/184 | 0.92 (0.72-1.19) | 236/251 | 0.92 (0.74-1.14) | ||||||||
| GG | 16/11 | 1.47 (0.66-3.30) | 17/15 | 1.06 (0.52-2.15) | 10/35 | 0.26 (0.12-0.54) | 21/33 | 0.64 (0.37-1.12) | ||||||||
NOTE: Analyzed by conditional logistic regression stratified by case-control sets.