Table 5.

CBMN frequency (‰) in coke-oven and non–coke-oven workers by phenotypes of mEH and NAT2

PhenotypeNon–coke-oven workers
Coke-oven workers
P*
nMean ± SDPnMean ± SDP
mEH
    LA394.1 ± 3.9Reference708.6 ± 6.8Reference<0.01
    IA233.3 ± 2.80.56559.6 ± 6.00.17<0.01
    HA46.8 ± 4.30.091613.2 ± 6.70.010.10
    IA-HA273.8 ± 3.20.967110.4 ± 6.30.04<0.01
NAT2
    Fast acetylator273.9 ± 3.1Reference608.5 ± 5.5Reference<0.01
    Slow acetylator394.1 ± 3.90.928110.4 ± 7.20.43<0.01
  • * Mann-Whitney U tests for the differences in CBMN frequencies between coke-oven workers and non–coke-oven workers by each genotype.

  • Multivariate analysis of covariance tests for differences in ln-transformed CBMN data between genotypes with adjustment for urinary 1-OHP, age, sex, and cigarettes per day in coke-oven workers and non–coke-oven workers separately.

  • Reference group for comparisons of ln-transformed CBMN data between genotypes.