Table 2

Polymorphisms of ER-αPvuII and XbaI and breast cancer risk, Shanghai Breast Cancer Study, 1996–1998

Case (%) (n = 1069)Control (%) (n = 1166)ORa95% CIFAR 95% CI
PvuII
 PP12.916.31.0(ref)b
 Pp/pp87.183.71.4(1.1–1.7)
  Pp48.346.81.3(1.0–1.7)(1.2–1.5)
  pp38.836.91.4(1.1–1.8)(1.2–1.6)
Trend testP = 0.042
XbaI
 XX3.44.21.0(ref)
 Xx/xx96.695.81.2(0.8–1.9)
  Xx46.543.61.3(0.8–2.0)(1.1–1.4)
  xx50.152.31.2(0.7–1.8)(1.0–1.3)
Trend testP = 0.660
PvuII and XbaI
 PPXX2.73.21.0(ref)
 PPXx8.09.51.0(0.6–1.7)(0.7–1.3)
 PPxx2.33.70.7(0.3–1.4)(0.4–1.2)
 PpXX0.60.71.0(0.3–3.4)(0.4–3.0)
 PpXx27.927.21.2(0.7–2.0)(1.0–1.4)
 Ppxx19.718.81.3(0.7–2.1)(1.0–1.5)
 ppXX00-
 ppXx10.67.31.7(1.0–3.1)(1.3–2.3)
 ppxx28.229.61.1(0.7–1.9)(1.0–1.3)
  • a Adjusted for age.

  • b ref., reference.