Table 3

Association of AR exon 1 CAG_n polymorphism with breast cancer

	Mean of alleles cut-off							Long allele cut-off
		No. ≤25	No. >25	Crude ORs (95% CI)	Adjusted^a ORs (95% CI)	No. ≤25	No. >25	Crude ORs (95% CI)	Adjusted^a ORs (95% CI)
All women
Cases	242	57	0.47 (0.28–0.8)	0.47 (0.24–0.94)	183	116	0.56 (0.39–0.81)	0.43 (0.26–0.71)
Controls	206	23			169	60
Age group
<50
Cases	197	42	0.56 (0.32–0.98)	0.58 (0.27–1.23)	146	93	0.59 (0.40–0.89)	0.45 (0.26–0.76)
Controls	176	21			143	54
50+
Cases	45	15	0.2 (0.04–0.94)	0.2 (0.03–1.15)	37	23	0.37 (0.13–1.04)	0.35 (0.08–1.39)
Controls	30	2			26	6
Menopause
Premenopausal
Cases	181	40	0.44 (0.23–0.82)	0.39 (0.17–0.91)	135	86	0.6 (0.39–0.92)	0.38 (0.21–0.68)
Controls	156	15			124	47
Postmenopausal
Cases	56	16	0.36 (0.11–1.16)	0.39 (0.08–1.75)	45	27	0.44 (0.18–1.06)	0.43 (0.12–1.56)
Controls	39	4			34	9
Family history^b
Yes
Cases	32	4	—	—	25	11	0.67 (0.2–2.27)	0.67 (0.14–3.08)
Controls	22	0			17	5
No
Cases	192	49	0.38 (0.2–0.7)	0.42 (0.2–0.89)	146	95	0.52 (0.34–0.8)	0.38 (0.22–0.66)
Controls	156	15			128	43

^a Adjusted for age at menarche, age at first birth, age at last birth, oral contraceptive use, and smoking.
^b Family history of breast or ovarian cancer, includes only subjects for whom this information was available.