Table 1

Age, body mass index, urinary aMT6S, creatinine, and creatinine-adjusted urinary aMT6S over time (n = 40)

t1 Mean (CI)at2 Mean (CI)Difference t2-t1 (%)t3 Mean (CI)Difference t3-t1 (%)Pb
Age (years)57.6 (56.0–59.1)58.6 (57.1–60.2)1.0 (1.8)62.7 (61.1–64.2)5.1 (8.8)NA
BMI (kg/m2)25.7 (24.6–26.9)25.6 (14.4–26.8)−0.1 (0.4)26.3 (25.2–27.5)0.6 (2.3)0.035c
aMT6Sd (mg/l)11.00 (8.28–14.62)8.09 (6.08–10.75)−2.9 (−26.5)7.04 (5.30–9.36)−4.0 (−36.0)0.005
Creatinined (mg/l)818.6 (732.3–915.1)788.6 (705.4–881.5)−30.0 (−3.7)727.0 (650.3–812.7)−91.6 (−11.2)0.144
Adjusted aMT6Sd (ng/mg creatinine)13.44 (10.49–17.22)10.25 (8.00–13.14)−3.2 (−23.7)9.69 (7.56–12.41)−3.8 (−27.9)0.013
  • a CI, confidence interval; t1, timepoint 1; t2, timepoint 2; t3, timepoint 3.

  • b Test for heterogeneity using Greenhouse-Geisser’s ε as the correction factor for repeated measures.

  • c If Box’s more conservative ε is used, this relationship becomes nonsignificant at the 5% level, P = 0.059.

  • d Geometric means and 95% CI.