Table 1

Genes that show more than three-fold differences in expression in ascending versus descending adult colon

GeneCloneUniGene clusterFold-difference L:ATat value
homeo box D13 IncytePD:3462557Hs.1583098.155.932
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 IncytePD:1634540Hs.1023075.716.656
serine protease inhibitor, Kazal type, 5 IncytePD:776793Hs.3315555.396.606
ESTs IncytePD:1671596Hs.1094385.2317.146
secretory leukocyte protease inhibitor (antileukoproteinase) IncytePD:2510171Hs.2517544.5215.136
homeo box B13 IncytePD:1861743Hs.667314.317.999
BRCA1 associated protein IncytePD:1623214Hs.1227644.069.395
connective tissue growth factor IncytePD:1674454Hs.755114.038.561
EGF-containing fibulin-like extracellular matrix protein 1 IncytePD:1798209Hs.762244.0311.436
protease inhibitor 3, skin-derived (SKALP) IncytePD:2503913Hs.1123413.937.209
NADPH oxidase 1 IncytePD:2793437Hs.1323703.886.904
solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IncytePD:1632811Hs.1936653.734.161
retinoic acid receptor responder (tazarotene induced) 2 IncytePD:1988108Hs.376823.7211.839
sialyltransferase 1 (β-galactoside α-2,6-sialyltransferase) IncytePD:3211926Hs.3745283.666.651
osteoblast specific factor 2 (fasciclin I-like) IncytePD:1994715Hs.1363483.514.614
cysteine-rich protein 1 (intestinal) IncytePD:2121863Hs.31923.411.104
S100 calcium binding protein P IncytePD:2060823Hs.29623.395.728
CMP-NeuAC:(β)-N-acetylgalactosaminide (alpha)2,6-sialyltransferase member VIIncytePD:2504517Hs.1096723.3210.432
family with sequence similarity 3, member C IncytePD:1926135Hs.298823.3212.324
cysteine-rich, angiogenic inducer, 61 IncytePD:1514989Hs.88673.285.845
phospholipase A2, group IIA (platelets, synovial fluid) IncytePD:699410Hs.764223.276.014
protein phosphatase 1, regulatory (inhibitor) subunit 12B IncytePD:1998571Hs.1307603.1818.759
somatostatin IncytePD:2494617Hs.124093.114.037
chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) IncytePD:1669647Hs.2373563.0811.331
alpha-actinin-2-associated LIM proteinIncytePD:1924344Hs.1352813.0514.464
ribonuclease, RNase A family, 1 (pancreatic) IncytePD:3086929Hs.782243.019.321
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) IncytePD:1807407Hs.598890.33−8.154
acyl-Coenzyme A oxidase 1, palmitoyl IncytePD:1798585Hs.3799910.33−13.088
carnitine deficiency-associated gene expressed in ventricle 1 IncytePD:1494531Hs.3331200.33−3.798
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme IncytePD:1966455Hs.9340.32−7.262
MAWD binding protein IncytePD:1812030Hs.163410.32−4.875
glypican 3 IncytePD:645584Hs.1196510.32−6.347
ATP-binding cassette, sub-family G (WHITE), member 2 IncytePD:1501080Hs.1947200.32−8.077
solute carrier family 38, member 4 IncytePD:778212Hs.1656550.3−6.679
homeo box B6 IncytePD:606814Hs.984280.3−6.918
solute carrier family 16 (monocarboxylic acid transporters), member 1 IncytePD:1981569Hs.752310.29−13.71
differentially expressed in hematopoietic lineages IncytePD:1903267Hs.2733210.28−5.393
solute carrier family 16 (monocarboxylic acid transporters), member 1 IncytePD:733668Hs.752310.26−12.558
hydroxy-δ-5-steroid dehydrogenase, 3 β- and steroid δ-isomerase 1 IncytePD:182802Hs.385860.24−6.071
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 IncytePD:1634063Hs.5600.24−5.824
cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18 IncytePD:25957280.22−7.491
solute carrier family 20 (phosphate transporter), member 1 IncytePD:1846463Hs.784520.2−16.061
hydroxy-δ-5-steroid dehydrogenase, 3 β- and steroid δ-isomerase 2 IncytePD:942100Hs.8250.2−5.632
nuclear receptor subfamily 1, group H, member 4 IncytePD:214180Hs.1716830.16−9.444
alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) IncytePD:2771046Hs.12390.15−7.824
paired-like homeodomain transcription factor 2 IncytePD:2794019Hs.922820.13−8.926
regenerating islet-derived 1 α (pancreatic stone protein, pancreatic thread protein) IncytePD:2923150Hs.10320.11−8.678
meprin A, βIncytePD:2234609Hs.1947770.08−15.037
ethanolamine kinase IncytePD:2718565Hs.1204390.07−19.742
  • a L:AT, ratio of descending colon to ascending colon.