Table 5

Total calcium and prostate cancer risk by PSA test, Nutrition Cohort, 1992–1997

PSA
No PSA before 1992PSA before 1992
Total calcium
<700 mg/day
 No. of cases787335
 Person-years87,12727,467
 RR (95% CI)a11
 RR (95% CI)b11
700–999 mg/day
 No. of cases726374
 Person-years78,76729,489
 RR (95% CI)a1.0 (0.9–1.1)1.0 (0.9–1.2)
 RR (95% CI)b0.9 (0.8–1.1)0.9 (0.8–1.1)
1000–1499 mg/day
 No. of cases451268
 Person-years49,38620,962
 RR (95% CI)a0.9 (0.8–1.1)1.0 (0.8–1.2)
 RR (95% CI)b1.0 (0.8–1.2)0.9 (0.7–1.2)
1500–1999 mg/day
 No. of cases15476
 Person-years12,9235,723
 RR (95% CI)a1.2 (1.0–1.4)1.0 (0.8–1.3)
 RR (95% CI)b1.4 (1.1–1.8)1.0 (0.7–1.4)
2000+ mg/day
 No. of cases5927
 Person-years4,5521,924
 RR (95% CI)a1.3 (1.0–1.7)1.1 (0.7–1.6)
 RR (95% CI)b1.5 (1.1–2.0)1.0 (0.6–1.6)
P for trendb,cP trend < 0.01P trend = 0.93
  • a Adjusted for age at entry, race.

  • b Adjusted for age at entry, race, family history of prostate cancer, total energy, total fat intake, education, phosphorus, total vitamin D.

  • c P for homogeneity of trends: P < 0.01.