Table 3

Stratification analysis of the XRCC1 399 genotype and the frequency of p53 gene mutation

VariableGln/GlnGln/Arg and Arg/Arg
Mutations detected/tumors tested (%)OR (95% CI)Mutations detected/tumors tested (%)OR (95% CI)
Smoking
 Yes12/17 (70.59)3.20 (0.83–12.40)78/193 (40.41)0.90 (0.36–2.23)
 No2/2 (100.00)∞ (0.21–∞)a9/21 (42.86)1
Alcohol drinking
 Yes9/10 (90.00)19.24 (2.33–159.11)58/124 (46.77)1.88 (1.07–3.30)
 No5/9 (55.56)2.67 (0.67–10.69)29/91 (31.87)1
AQ chewing
 Yes11/16 (68.75)3.11 (0.91–10.58)70/174 (40.23)0.95 (0.48–1.90)
 No3/3 (100.00)∞ (0.52–∞)a17/41 (41.46)1
  • a Exact OR by EGRET.