Table 1

Association of breast pubertal stage T2B ≥2 with the number of high-activity alleles among 137 girls 9.5 years of agea

Reference alleleOdds trend95% CIP trend
CYP17*A1 1.440.80–2.630.2253
CYP1A2*1F WT 1.070.55–2.080.8444
CYP1B1*1 0.980.55–1.720.9830
CYP3A4*1A 3.21 1.62–6.89 0.0007
CYP3A5*3 1.450.75–2.870.2687
  • a ORs are for increasing number of gene variants (0, 1, 2) with trend indicated by the P. The test for lack-of-fit was not significant for any models.