Table 3

Studies examining intention to pursue genetic testing for breast cancer susceptibility among women at higher-than-average risk of breast cancer

StudyStudy populationNo. of patientsType of studyIntention to pursue testingKnowledge or awareness of testingCancer worryInsurance coverage
Lerman et al. (13)First-degree relatives of breast cancer patients105 (female)Telephone interviews91%Not testedNot testedNot tested
Struewing et al. (16)Breast-ovarian cancer family members140 (male and female)Structured interviews95%Not testedHigher perceived risk associated with intention to be testedNot tested
Richards et al. (15)Ashkenazi Jewish men and women309 (male and female)Questionnaires at educational session for testing94% requested testingNot testedNot testedNot tested
Lipkus et al. (14)African-American women with and without family history of breast cancer266Telephone interviews72% with family history vs. 58% with no family historyNot testedHigher perceived risk and concern associated with interest in testingNot tested
Durfy et al. (11)Women with family history of breast cancer543Telephone interviews82.9–89.9% depending on study groupNot testedCancer worry similar among Caucasian, African-American, Ashkenazi Jewish, and lesbian/bisexual womenAfrican Americans less interested if self-pay than Caucasians
Cappelli et al. (10)Women with and without personal history of breast cancer110Structured interviews72% with personal history; 46% from control groupNo associationNo associationNot tested
Kash et al. (12)Women part of a high-risk registry1007Questionnaire (method of implementation not given)72% would undergo testingInverse associationIncreased perception of breast cancer risk associated with increased interest in testingNot tested
Bottorff et al. (9)Women with and without personal breast cancer history1021Telephone interviews30.8% with personal history; 28.5% of control groupPositive associationNot testedNot tested (Canadian study)