Table 2

Mean plasma levels of IGF-1, IGFBP-3, and IGF-1:IGFBP-3 molar ratio by intake of nutrients in quintiles in male health professionals

NutrientaMedian daily intakeIGF-1 (ng/mL)IGFBP-3 (ng/mL)IGF-1:IGFBP-3 (molar ratio)
Total Fat (g)
47.818831290.234
58.418432180.225
66.718130690.230
74.018631290.232
84.017930580.227
P (trend)(0.16)(0.24)(0.54)
Carbohydrate (g)
192.618132090.220
232.818430870.233
254.817931130.226
277.918530580.236
310.018931680.232
P (trend)(0.13)(0.97)(0.04)
Protein (g)
69.117330820.220
79.517730430.227
85.918230810.230
93.818731780.230
107.120132570.242
P (trend)(<0.0001)(0.01)(<0.0001)
Animal protein (g)
39.216830420.217
51.318131130.226
59.118130320.233
67.219031900.231
81.720032730.241
P (trend)(<0.0001)(0.01)(<0.0001)
Vegetable protein (g)
20.217331140.217
23.918330860.230
27.017931000.228
30.019132240.231
36.019431260.242
P (trend)(<0.0002)(0.59)(<0.0001)
  • a Protein, carbohydrate, and fat are adjusted for total energy. All results are adjusted for age and laboratory run. Animal and vegetable protein intakes are adjusted for each other.