Table 1

Mean plasma levels of IGF-1, IGFBP-3, and IGF-1:IGFBP-3 molar ratio by intakes of energy (quintiles) in 753 male health professionals

Caloriesa median daily intake(n)IGF-1 (ng/mL)IGFBP-3 (ng/mL)IGF-1:IGFBP-3 (molar ratio)
Total Population
 122616118231500.226
 153613418131170.227
 186014218130780.228
 217315818430800.234
 278415818931940.231
P (trend)(0.22)(0.45)(0.29)
BMI <25 kg/m2
 12517118031730.222
 15365917729770.233
 18345418531550.230
 21927219031930.234
 27626219632680.231
P (trend)(0.03)(0.12)(0.27)
BMI ≥25 kg/m2
 12079018531450.229
 15367518231740.224
 18748817729960.228
 21398617829680.234
 27849618531290.232
P (trend)(0.94)(0.80)(0.62)
  • a Calories exclude those from alcohol intake. All results are adjusted for age and laboratory run.