Mean ± SD of baseline characteristics of the 191 study subjects by the VDR FokI genotype
| Variable | VDR FokI genotype | Pa | ||||
|---|---|---|---|---|---|---|
| FF | Ff | ff | ||||
| No. of subjects (%) | 78 (41%) | 73 (38%) | 40 (21%) | |||
| Age at surgery (yrs) | 64.8 ± 6.8 | 65.2 ± 6.5 | 63.2 ± 6.2 | 0.28 | ||
| % Gleason grade 4/5 | 42.8 ± 30.0 | 43.8 ± 30.2 | 30.3 ± 28.6 | 0.05b | ||
| Index cancer volume (cc) | 5.2 ± 5.3 | 5.3 ± 5.7 | 5.7 ± 6.0 | 0.88 | ||
| Preoperative serum PSA (ng/ml) | 24.5 ± 39.5 | 19.7 ± 23.2 | 18.5 ± 14.1 | 0.49 | ||
a By ANOVA.
b P = 0.015 by t test when the FF and Ff genotypes were combined and compared with the ff genotype.