Table 2

Distribution of GSTM1, GSTT1, GSTP1 (ILE105VAL), and CYP1A1 (ILE462VAL) genotypes among head and neck cancer cases and controls

Ref.Country% GSTM1 null% GSTT1 null% GSTP1 any Val% CYP1A1 any Val
CasesControlsCasesControlsCasesControlsCasesControls
Asia
(13) India49.224.718.212.2
(47) India49.033.318.48.351.016.7
(29 , 30) Japan58.746.347.851.037.323.8a45.739.5
(32) Japan55.148.7
(37) Japan49.050.624.831.133.836.6
(38) Japan67.045.5
(46) Japan64.845.152.136.6
(48) Japan43.042.0
(22) Korea68.352.457.336.5
(23) Taiwan58.557.758.552.8
(28) Taiwan86.854.8a
(31) Thailand56.630.234.047.2
Overall in Asia55.041.730.927.729.328.052.739.5
 Europe
(15) France69.248.6
(25 26 27) France54.452.320.415.755.250.0
(18) Germany42.848.916.015.117.113.7
(19) Germany59.653.34.36.7
(33) Germany53.248.320.520.3
(34 , 35) Germany57.453.422.022.255.046.9a15.014.5
(45) Germany51.853.815.513.9
(40 , 41) Netherlands50.851.719.520.350.656.118.416.4a
(24) Poland49.157.817.521.7
(17) Spain58.751.5
(49) Spain47.149.317.223.650.750.2
(16) United Kingdom55.054.811.818.5
Overall in Europe52.752.419.319.653.351.415.013.8
 North America
(20) Canada56.757.822.210.0
(14) United States53.142.932.717.5
(21) United States80.050.015.020.0
(36) United States46.346.516.918.358.953.26.514.0
(39) United States43.644.618.613.566.361.17.65.8
(42 43 44) United States43.336.362.364.617.67.6a
(50) United States68.347.644.935.7
Overall in North America52.543.126.516.862.760.99.47.8
 Overall53.347.022.920.652.750.623.921.1
  • a Departure from Hardy–Weinberg equilibrium detected (P < 0.05). Hardy–Weinberg equilibrium was assessed among the controls for GSTP1 and CYP1A1.