Table 1

Summary of case–control studies on GSTM1, GSTT1, GSTP1 (ILE105VAL), and CYP1A1 (ILE462VAL) genotypes and head and neck cancers

Ref.First authorYear of publicationCountryControl sourceMatchingSite
OralPharynxLarynx
(13) Buch2002IndiaHospital-healthyIndividualX
(14) Cheng1999United StatesHospitalIndividualHead & neck; site NS
(15) Coutelle1997FranceAlcoholism clinicNoneXX
(16) Deakin1996United KingdomHospitalNoneX
(17) Gonzalez1998SpainHospital-healthyNoneXXX
(18) Gronau2003GermanyHospital-healthyIndividualXXX
(19) Hahn2002GermanyHospital-healthyIndividualX
(20) Hamel2000CanadaMixedIndividualXXX
(21) Hanna2001United StatesHospitalIndividualX
(22) Hong2000KoreaHospitalNoneX
(23) Hung1997TaiwanPopulation basedFrequencyX
(24) Jaskula-Sztul1998PolandNS, healthyNoneX
(25 , 26) Jourenkova1999FranceHospitalFrequencyXXX
(26 , 27) Jourenkova1999FranceHospitalFrequencyXXX
(28) Kao2002TaiwanHospitalNoneX
(29) Katoh1999JapanHospital-healthyNoneX
(30) Katoh1999JapanHospital-healthyNoneX
(31) Kietthubthew2001ThailandPopulation basedIndividualX
(32) Kihara1997JapanHospital-healthyNoneXXX
(33) Ko2001GermanyHospital-healthyNoneHead & neck; site NS
(34) Matthias1998GermanyHospitalNoneXXX
(35) Matthias1999GermanyHospitalNoneXXX
(36) McWilliams2000United StatesHospitalNoneXXX
(37) Morita1999JapanHospital-healthyNoneXXX
(38) Nomura2000JapanHospitalNoneXX
(39) Olshan2000United StatesHospitalFrequencyXXX
(40) Oude Ophuis1998NetherlandsHospital-healthyNoneXXX
(41) Oude Ophuis2003NetherlandsHospital-healthyNoneXXX
(42) Park1997United StatesHospitalFrequencyXXX
(43) Park1999United StatesHospitalFrequencyXXX
(44) Park2000United StatesHospitalFrequencyXXX
(45) Risch2003GermanyPopulation basedFrequencyX
(46) Sato2000JapanHospital-healthyNoneX
(47) Sreelekha2001IndiaHospital-healthyIndividualX
(48) Tanimoto1999JapanHospitalIndividualX
(49) To-Figueras2002SpainHospital-healthyNoneX
(50) Trizna1995United StatesHospital-healthyNoneXXX
No. of studies in meta-analysis
Cases
Controls
Summary OR (95% CI)
Test for heterogeneity
Publication bias (Egger’s test)