Expression of hMLH1 and hMSH2 and hMLH1 promoter methylation statusa N (%)
| All tumors (n = 184) | MSI-H (n = 40) | MSI-L/MSS (n = 144) | Hypermethylation | |||
|---|---|---|---|---|---|---|
| Yes (n = 20) | No (n = 17) | |||||
| hMLH1 absent | 26 (14) | 26 (65) | 0 | 17 (85) | 7 (41) | |
| hMSH2 absent | 6 (3) | 6 (15) | 0 | 0 | 6 (35) | |
| hMLH1 and hMSH2 present | 152 (83) | 8 (20) | 144 (100) | 3 (15) | 4 (24) | |
a The hMLH1 promoter methylation status of three MSI-H tumors could not be determined.