Table 3

Joint effect of hOGG1 codon 326 and XRCC1 codon 280 and NPC risk

Gene-gene grouping hOGG1 codon 326XRCC1 codon 280NPC case patientsCommunity control subjectsUnadjusted ORAdjusteda OR (95% CI)
Ser/Ser Arg/His + His/His5111.01.0
Ser/Ser Arg/Arg 31351.91.9 (0.59–6.2)
Ser/Cys + Cys/CysArg/His + His/His52572.02.0 (0.63–6.1)
Ser/Cys + Cys/Cys Arg/Arg 2431803.0b3.0 (1.0–8.8)
  • a OR estimates adjusted for age, gender, and ethnicity.

  • b Indicates unadjusted ORs in which 95% CI excludes 1.0.