Table 1

Distribution of hOGG1 codon 326, XRCC1 codon 280, and XRCC1 codon 399 in different ethnic groups among 283 community controls

Grouping of DNA repair genesFukien no. (%)Hakka no. (%)Other no. (%)Hardy-Weinberg equilibrium χ2P
hOGG1 codon 326
Ser/Ser33 (16.5)3 (16.7)10 (15.4)
Ser/Cys89 (44.5)10 (55.6)30 (46.2)
Cys/Cys78 (39.0)5 (27.8)25 (38.5)>0.05
Cys allele frequency0.610.560.62
XRCC1 codon 280
Arg/Arg147 (73.5)17 (94.4)51 (78.5)
Arg/His51 (25.5)1 (5.6)14 (21.5)
His/His2 (1.0)0 (0.0)0 (0.0)>0.05
His allele frequency0.140.030.11
XRCC1 codon 399b
Arg/Arg109 (54.8)8 (44.4)35 (53.9)
Arg/Gln74 (37.2)9 (50.0)26 (40.0)
Gln/Gln16 (8.0)1 (5.6)4 (6.2)>0.05
Gln allele frequency0.270.310.26
  • a‘Other’ included the aboriginal, Cantonese, and other Han origins.

  • b The genotype of one subject couldn’t be identified.