Table 6

Expression of OGG1 and ERCC1 mRNA relative to 18S in leukocytes isolated from whole blood (mean and SD with number of subjects in parenthesis)a,b

DietBeforeDay 9Day 16Day 24Afterc
Expression of OGG1 mRNA
 Placebo10.0 ± 5.3 (15)9.5 ± 5.9 (15)7.6 ± 4.6 (9)10.5 ± 6.7 (16)11.0 ± 6.8 (13)
 Vitamin7.2 ± 2.9 (11)6.9 ± 3.5 (12)6.7 ± 2.7 (9)7.3 ± 3.0 (12)10.9 ± 7.3 (12)
 Vegetable8.9 ± 4.1 (15)11.1 ± 6.6 (15)6.3 ± 1.6 (11)9.0 ± 6.5 (15)9.8 ± 9.0 (13)
Expression of ERCC1 mRNA
 Placebo29.0 ± 14.6 (14)28.3 ± 12.9 (14)24.8 ± 13.6 (9)33.6 ± 18.5 (15)41.6 ± 28.0 (12)
 Vitamin22.9 ± 6.5 (11)23.7 ± 7.9 (12)20.6 ± 6.5 (9)27.1 ± 11.5 (12)36.5 ± 17.9 (12)
 Vegetable29.0 ± 13.1 (15)31.4 ± 17.1 (15)19.9 ± 6.9 (11)28.8 ± 18.4 (15)30.9 ± 15.9 (13)
  • a The data are expressed as mRNA relative to the expression of 18S (per million).

  • b There were no interaction between the diets consumed and time point in the study, nor were there any single factor effects of the diet consumed and time point in the study.

  • c The “after” samples were obtained 4 weeks after cessation of the intervention period (day 52).