Table 4

Multivariate-adjusteda ORs and 95% CIs for breast cancer in relation to lipid-adjustedb log-transformed serum levels of organochlorine compounds stratified by parity and breastfeeding history among breast cancer cases and controls, Long Island Breast Cancer Study Project, 1996–1997

Parity and breastfeeding historyOrganochlorine compoundTertile cutpoints (ng/g lipid)Cases, nControls, nMultivariate-adjusted
OR(95% CI)
Nulliparous womenDDE<458.2526191.00
458.26–951.822991.69(0.59–4.82)
951.83–11,818.7825170.75(0.24–2.40)
Peak-4 PCBs<308.3426181.00
308.35–472.452181.55(0.53–4.56)
462.46–3,287.3432191.22(0.42–3.50)
Chlordane<79.1821221.00
79.19–125.532292.36(0.84–6.68)
125.54–473.0828112.83(0.93–8.65)
Parous women, never breastfedDDE<458.2589571.00
458.26–951.82105810.82(0.52–1.28)
951.83–11,818.78136761.14(0.70–1.84)
Peak-4 PCBs<308.34113641.00
308.35–472.45107770.74(0.48–1.14)
462.46–3,287.34107720.79(0.50–1.26)
Chlordane<79.1883591.00
79.19–125.53100681.02(0.64–1.63)
125.54–473.08119751.03(0.64–1.65)
Parous women, ever breastfedDDE<458.2587631.00
458.26–951.8253490.66(0.38–1.13)
951.83–11,818.7873460.96(0.51–1.80)
Peak-4 PCBs<308.3475561.00
308.35–472.4563520.86(0.51–1.44)
462.46–3,287.3473471.12(0.63–2.00)
Chlordane<79.1874481.00
79.19–125.5364510.77(0.45–1.31)
125.54–473.0865450.79(0.44–1.44)
  • a DDE and Peak-4 PCB analyses were adjusted for age, race, history of fertility problems, and history of benign breast disease. Chlordane analyses were adjusted for age, race, history of fertility problems, and gravidity.

  • b Adjusted using method 2 as described by Phillips et al. (50) .