Table 3

Distribution of the p16 exon 3 haplotype genotype and allele frequency in SCCHN patients and controls

p16 HaplotypeCases (n = 208)Controls (n = 224)
Number%Number%
Genotypesa
 540C-580C/540C-580C13464.413660.7
 540C-580C/540C-580T2512.03415.2
 540C-580C/540G-580C3818.34620.5
 540C-580T/540G-580C83.931.3
 540C-580T/540C-580T10.520.9
 540G-580C/540G-580C21.231.3
 540C-580C/540G-580T0000
 540G-580C/540G-580T0000
 540C-580T/540G-580T0000
 540G-580T/540G-580T0000
Allele frequenciesb
 CTCCGG……GGCCAC33179.635278.6
 CTCGGG……GGCCAC5012.05512.3
 CTCCGG … … GGCTAC358.4419.1
 CTCGGG … … GGCTAC0000
Total alleles416100448100
  • a For the p16 C540G/C580T haplotype genotype distribution: χ2 = 4.369, df = 5, P = 0.574.

  • b For the haplotype allele distribution: χ2 = 0.173, df = 2, P = 0.917.